Structure Exploring, IR and UV Spectroscopic Properties of Pomalidomide as a Second-generation of Immunomodulatory Agent

Authors

  • Farzaaneh Zaarei Department of Pharmaceutics,Faculty of Pharmacy,Tehran Universityof Medical Scienses,Tehran, Iran
  • Fatemeh Ebrahimi Shaghaghi Department of Biology, Scienceand Research Branch, Islamic Azad University, Tehran, Iran
  • Rahimeh Rasouli Department of Medical Nanotechnology, International Campus, Tehran University of Medical Sciences, Tehran, Iran
  • Reza Ghiasi Department of Chemistry, Faculty of science, East Tehran branch, Islamic Azad University, Qiam Dasht, Tehran, Iran
Abstract:

In this article, the optimized geometry, IR and UV spectra, frontier orbital analysis, natural bond orbital (NBO) analyses, and thermodynamic parameters of pomalidomide were investigated. The calculated structural parameters and stretching frequencies values are compared with experimentalvalues of the investigated compound. Also, the relations of the thermodynamic functions vs.temperatures were fitted by quadratic formulas.

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Journal title

volume 11  issue 2

pages  23- 38

publication date 2017-06-01

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